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Aspartate Aminotransferase (AST)

Blood

Aspartate Aminotransferase (AST)

Also known as: SGOT, GOT

COMMON RANGE

8 – 48

U/L

0

178

M

Mayo Clinic Laboratories

Adult Male

See all sources ↓

CONVERT & COMPARE

U/L

=

0.467

µkat/L

Reference ranges by source

Published adult intervals: 11, from 6 named sources, shown in U/L.

SOURCE

SEX

AGE

RANGE

VISUAL

CITE

M

Mayo Clinic Laboratories

Male

≥18y

8 – 48 U/L

M

Mayo Clinic Laboratories

Female

≥18y

8 – 43 U/L

R

RCPA / AACB Australasian Harmonised Reference Intervals

Male

≥18y

5 – 35 U/L

R

RCPA / AACB Australasian Harmonised Reference Intervals

Female

≥18y

5 – 30 U/L

N

Nordic Reference Interval Project

Male

≥18y

15 – 45 U/L

N

Nordic Reference Interval Project

Female

≥18y

15 – 35 U/L

J

JSCC / JAMT Japan

All

≥18y

13 – 30 U/L

#

NUMBER: Dutch Reference Value Study

Male

≥18y

14 – 43 U/L

#

NUMBER: Dutch Reference Value Study

Female

≥18y

13 – 38 U/L

T

Turkey Nationwide Reference Intervals

Male

≥18y

13 – 30 U/L

T

Turkey Nationwide Reference Intervals

Female

≥18y

11 – 25 U/L

M

Mayo Clinic Laboratories

Male · ≥18y

8 – 48 U/L

M

Mayo Clinic Laboratories

Female · ≥18y

8 – 43 U/L

R

RCPA / AACB Australasian Harmonised Reference Intervals

Male · ≥18y

5 – 35 U/L

R

RCPA / AACB Australasian Harmonised Reference Intervals

Female · ≥18y

5 – 30 U/L

N

Nordic Reference Interval Project

Male · ≥18y

15 – 45 U/L

N

Nordic Reference Interval Project

Female · ≥18y

15 – 35 U/L

J

JSCC / JAMT Japan

All · ≥18y

13 – 30 U/L

#

NUMBER: Dutch Reference Value Study

Male · ≥18y

14 – 43 U/L

#

NUMBER: Dutch Reference Value Study

Female · ≥18y

13 – 38 U/L

T

Turkey Nationwide Reference Intervals

Male · ≥18y

13 – 30 U/L

T

Turkey Nationwide Reference Intervals

Female · ≥18y

11 – 25 U/L

Ages 0–17 (CALIPER)

6 age- and sex-stratified entries from the Canadian Laboratory Initiative on Pediatric Reference Intervals.

SOURCE

SEX

AGE

RANGE

VISUAL

CITE

C

CALIPER: Canadian Pediatric Reference Intervals

All

0–15d

32 – 162 U/L

C

CALIPER: Canadian Pediatric Reference Intervals

All

15d–1y

20 – 67 U/L

C

CALIPER: Canadian Pediatric Reference Intervals

All

1y–7y

21 – 44 U/L

C

CALIPER: Canadian Pediatric Reference Intervals

All

7y–12y

18 – 36 U/L

C

CALIPER: Canadian Pediatric Reference Intervals

Female

12y–19y

13 – 26 U/L

C

CALIPER: Canadian Pediatric Reference Intervals

Male

12y–19y

14 – 35 U/L

C

CALIPER: Canadian Pediatric Reference Intervals

All · 0–15d

32 – 162 U/L

C

CALIPER: Canadian Pediatric Reference Intervals

All · 15d–1y

20 – 67 U/L

C

CALIPER: Canadian Pediatric Reference Intervals

All · 1y–7y

21 – 44 U/L

C

CALIPER: Canadian Pediatric Reference Intervals

All · 7y–12y

18 – 36 U/L

C

CALIPER: Canadian Pediatric Reference Intervals

Female · 12y–19y

13 – 26 U/L

C

CALIPER: Canadian Pediatric Reference Intervals

Male · 12y–19y

14 – 35 U/L

About Aspartate Aminotransferase (AST)

An AST blood test measures the amount of AST in your blood. This test is commonly used to help diagnose liver damage or disease.

AST (aspartate aminotransferase) is an enzyme, a protein that speeds up certain chemical reactions in your body. It is found mainly in your liver but also in your heart, muscles, and other tissues. Usually, you will have low levels of AST in your blood. When your liver or other cells that contain AST are damaged, they release AST into your blood. This can lead to high AST levels in your blood.

An AST test may be ordered by itself but is often ordered as part of a group of liver function tests.

Main source: MedlinePlus ↗

Useful for

An AST blood test is often part of a routine blood screening to check the health of your liver

The test may help diagnose or monitor liver problems

It may also help diagnose other health conditions

Main source: MedlinePlus ↗

Interpretation

Low levels of AST in the blood are usually considered normal.

High levels of AST in the blood may be due to liver disease or other liver problems, and can also be related to other conditions affecting tissues that contain AST.

If your results are not in the normal range, it doesn't always mean that you have a medical condition that needs treatment. Many things can affect your results, such as pregnancy, exercise, certain medicines, and your age or sex. Talk with your provider to learn what your results mean.

For general wellness information only. Talk to a clinician about your specific results.

Main source: MedlinePlus ↗

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Related biomarkers

More tests in the blood category.

White Blood Cells (WBC)

Red Blood Cells (RBC)

Hemoglobin (Hgb)

Hematocrit (Hct)

Platelets (PLT)

Mean Corpuscular Volume (MCV)

Sources

Mayo Clinic Laboratories

RCPA / AACB Australasian Harmonised Reference Intervals

Nordic Reference Interval Project

J

JSCC / JAMT Japan

NUMBER: Dutch Reference Value Study

T

Turkey Nationwide Reference Intervals

CALIPER: Canadian Pediatric Reference Intervals

Last updated 2026-05-02

This page presents source-specific reference data and sourced explanations. For general wellness information only. This is not medical advice. For diagnosis or treatment of any condition, talk to a qualified clinician.

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