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D-Dimer

Blood

D-Dimer

Also known as: DD

COMMON RANGE

0 – 500

ng/mL

1100

Mayo Clinic Laboratories

Adult

↗

See all sources ↓

CONVERT & COMPARE

ng/mL

0.25

µg/mL

0.25

mg/L

250

µg/L

250

mcg/L

250

ug/L

0.25

mcg/mL

0.25

ug/mL

Reference ranges across 10+ sources

Adult reference ranges from 8 entries across 4 named sources, shown in ng/mL. Compare side-by-side.

SOURCE

SEX

AGE

RANGE

VISUAL

CITE

ARUP Laboratories

All

≥18y

0 – 400 ng/mL

↗

Mayo Clinic Laboratories

All

≥18y

0 – 500 ng/mL

↗

Quest Diagnostics

All

≥18y

0 – 500 ng/mL

↗

Labcorp

All

18y–50y

0 – 500 ng/mL

↗

Labcorp

All

51y–60y

0 – 600 ng/mL

↗

Labcorp

All

61y–70y

0 – 700 ng/mL

↗

Labcorp

All

71y–80y

0 – 800 ng/mL

↗

Labcorp

All

≥81y

0 – 1000 ng/mL

↗

ARUP Laboratories

All · ≥18y

↗

0 – 400 ng/mL

Mayo Clinic Laboratories

All · ≥18y

↗

0 – 500 ng/mL

Quest Diagnostics

All · ≥18y

↗

0 – 500 ng/mL

Labcorp

All · 18y–50y

↗

0 – 500 ng/mL

Labcorp

All · 51y–60y

↗

0 – 600 ng/mL

Labcorp

All · 61y–70y

↗

0 – 700 ng/mL

Labcorp

All · 71y–80y

↗

0 – 800 ng/mL

Labcorp

All · ≥81y

↗

0 – 1000 ng/mL

About D-Dimer

A D-dimer test looks for D-dimer in blood. D-dimer is a protein fragment (small piece) that's made when a blood clot dissolves in your body. Measuring it gives a sense of how active your body's clot-breakdown (fibrinolytic) system is and whether clots may be forming inside your blood vessels. D-dimer isn't usually found in your blood unless your body is making or breaking up blood clots.

A blood clot is a mass of blood that forms when platelets, proteins, and cells in the blood stick together. When you get hurt, your body forms a blood clot to stop the bleeding. Blood clotting is an important process that prevents you from losing too much blood when you are injured.

Normally, your body will dissolve the clot once your injury has healed. With a blood clotting disorder, clots can form when you don't have an injury, or they don't dissolve when they should. These disorders can be serious and even life-threatening.

D-dimer testing is especially useful for helping rule out a clot in a vein (venous thromboembolism) in people who are at higher risk.

Main source: MedlinePlus ↗

Useful for

Deep vein thrombosis (DVT), a blood clot that forms in a vein deep in your body. These clots usually affect the lower legs, but they can also happen in other parts of your body.

Pulmonary embolism (PE), a blockage in a lung artery. It usually happens when a blood clot in another part of your body breaks loose and travels to your lungs. DVT clots are a common cause of PE.

Disseminated intravascular coagulation (DIC), a condition that causes too many blood clots to form. They can form throughout the body, causing organ damage and other serious health issues. DIC may be caused by inflammation, infection, or cancer.

Stroke, which can happen when blood flow to a part of the brain is blocked.

Helps rule out a blood clot in people who are at higher risk for clots in the veins or lungs.

Main source: MedlinePlus ↗

Interpretation

If your results show low or normal D-dimer levels in the blood, it usually means a clot in a vein or the lungs is unlikely, especially if your provider already thinks the chance of a clot is low or moderate (this is called pretest probability). Combining a low pretest probability with a normal D-dimer can often safely rule out dangerous clots without imaging.

If you are being treated with blood-thinning medicines, they may cause a false-negative D-dimer test. This means your test results show that you don't have a clotting disorder, but you really do.

D-dimer naturally goes up with age, so providers sometimes use an age-adjusted cutoff (about your age in years multiplied by 10 ng/mL) for people over 50 to avoid unnecessary follow-up tests.

Higher than normal D-dimer can be a sign of a clotting problem, but it can also be raised by many other conditions, including infection, recent surgery or injury, hospital stays, cancer, liver disease, rheumatoid arthritis, heart disease, and pregnancy. Being older or unable to move around (immobilized) may also raise D-dimer. The level itself does not show how serious the condition is.

If your D-dimer is high, your provider will usually order imaging tests, such as an ultrasound of the legs or a CT scan of the lungs, to find out whether a clot is actually present and where it is.

For general wellness information only. Talk to a clinician about your specific results.

Main source: MedlinePlus ↗

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Related biomarkers

Often tested alongside d-dimer or part of the same panel.

White Blood Cells (WBC)

Blood

Red Blood Cells (RBC)

Blood

Hemoglobin (Hgb)

Blood

Hematocrit (Hct)

Blood

Platelets (PLT)

Blood

Mean Corpuscular Volume (MCV)

Blood

Sources

ARUP Laboratories

Mayo Clinic Laboratories

Quest Diagnostics

Labcorp

Last updated 2026-05-02

This page aggregates publicly available reference data and clinical information from Mayo Clinic Laboratories and other sources. For general wellness information only — not medical advice. For diagnosis or treatment of any condition, talk to a qualified clinician.

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